Amara was occupied by the Mesopotamian Expeditionary Force on 3 June 1915 and it immediately became a hospital centre. The accommodation for medical units on both banks of the Tigris was greatly increased during 1916 and in April 1917, seven general hospitals and some smaller units were stationed there.
Amara War Cemetery contains 4,621 burials of the First World War, more than 3,000 of which were brought into the cemetery after the Armistice. 925 of the graves are unidentified. In 1933, all of the headstones were removed from this cemetery when it was discovered that salts in the soil were causing them to deteriorate. Instead a screen wall was erected with the names of those buried in the cemetery engraved upon it. Plot XXV is a Collective Grave, the individual burial places within this are not known.
There are also seven non-war graves in the cemetery.